Cargando…

Advances in Cancer Treatment by Targeting the Neddylation Pathway

Developmental down-regulation protein 8 (NEDD8), expressed by neural progenitors, is a ubiquitin-like protein that conjugates to and regulates the biological function of its substrates. The main target of NEDD8 is cullin-RING E3 ligases. Upregulation of the neddylation pathway is closely associated...

Descripción completa

Detalles Bibliográficos
Autores principales: Gai, Wenbin, Peng, Zhiqiang, Liu, Cui Hua, Zhang, Lingqiang, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060460/
https://www.ncbi.nlm.nih.gov/pubmed/33898451
http://dx.doi.org/10.3389/fcell.2021.653882