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Advances in Cancer Treatment by Targeting the Neddylation Pathway

Developmental down-regulation protein 8 (NEDD8), expressed by neural progenitors, is a ubiquitin-like protein that conjugates to and regulates the biological function of its substrates. The main target of NEDD8 is cullin-RING E3 ligases. Upregulation of the neddylation pathway is closely associated...

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Detalles Bibliográficos
Autores principales:	Gai, Wenbin, Peng, Zhiqiang, Liu, Cui Hua, Zhang, Lingqiang, Jiang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060460/ https://www.ncbi.nlm.nih.gov/pubmed/33898451 http://dx.doi.org/10.3389/fcell.2021.653882

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