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Autophagy blockage promotes the pyroptosis of ox-LDL-treated macrophages by modulating the p62/Nrf2/ARE axis

Atherosclerosis, a chronic comprehensive cardiovascular disease, is characterized by the lipid infiltration, formation of foam cells derived from macrophages and inflammation in the vessel wall. Substantial evidence confirms that the activity of autophagic bodies plays a pivot role in regulating cel...

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Detalles Bibliográficos
Autores principales: Liu, Jiaru, Wang, Chao, Li, Jiashan, Yu, Ying, Liu, Yuee, Liu, Huihui, Peng, Qi, Guan, Xiuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060691/
https://www.ncbi.nlm.nih.gov/pubmed/33886081
http://dx.doi.org/10.1007/s13105-021-00811-2