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Autophagy blockage promotes the pyroptosis of ox-LDL-treated macrophages by modulating the p62/Nrf2/ARE axis
Atherosclerosis, a chronic comprehensive cardiovascular disease, is characterized by the lipid infiltration, formation of foam cells derived from macrophages and inflammation in the vessel wall. Substantial evidence confirms that the activity of autophagic bodies plays a pivot role in regulating cel...
Autores principales: | Liu, Jiaru, Wang, Chao, Li, Jiashan, Yu, Ying, Liu, Yuee, Liu, Huihui, Peng, Qi, Guan, Xiuru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060691/ https://www.ncbi.nlm.nih.gov/pubmed/33886081 http://dx.doi.org/10.1007/s13105-021-00811-2 |
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