Bdh2 Deficiency Promotes Endoderm-Biased Early Differentiation of Mouse Embryonic Stem Cells

3-hydroxybutyrate dehydrogenase-2 (Bdh2), a short-chain dehydrogenase, catalyzes a rate-limiting step in the biogenesis of the mammalian siderophore, playing a key role in iron homeostasis, energy metabolism and apoptosis. However, the function of Bdh2 in embryonic stem cells (ESCs) remains unknown....

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Detalles Bibliográficos
Autores principales: Fu, Yuting, Liu, Fangyuan, Cao, Shuo, Zhang, Jia, Wang, Huizhi, Wu, Baojiang, Song, Yongli, Duo, Shuguang, Li, Xihe, Bao, Siqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060705/
https://www.ncbi.nlm.nih.gov/pubmed/33898455
http://dx.doi.org/10.3389/fcell.2021.655145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060705/
https://www.ncbi.nlm.nih.gov/pubmed/33898455
http://dx.doi.org/10.3389/fcell.2021.655145

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