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Bdh2 Deficiency Promotes Endoderm-Biased Early Differentiation of Mouse Embryonic Stem Cells
3-hydroxybutyrate dehydrogenase-2 (Bdh2), a short-chain dehydrogenase, catalyzes a rate-limiting step in the biogenesis of the mammalian siderophore, playing a key role in iron homeostasis, energy metabolism and apoptosis. However, the function of Bdh2 in embryonic stem cells (ESCs) remains unknown....
Autores principales: | Fu, Yuting, Liu, Fangyuan, Cao, Shuo, Zhang, Jia, Wang, Huizhi, Wu, Baojiang, Song, Yongli, Duo, Shuguang, Li, Xihe, Bao, Siqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060705/ https://www.ncbi.nlm.nih.gov/pubmed/33898455 http://dx.doi.org/10.3389/fcell.2021.655145 |
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