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Targeting TFE3 Protects Against Lysosomal Malfunction-Induced Pyroptosis in Random Skin Flaps via ROS Elimination

Increasing evidence indicates that pyroptosis, a new type of programmed cell death, may participate in random flap necrosis and play an important role. ROS-induced lysosome malfunction is an important inducement of pyroptosis. Transcription factor E3 (TFE3) exerts a decisive effect in oxidative meta...

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Detalles Bibliográficos
Autores principales: Li, Jiafeng, Lou, Junsheng, Yu, Gaoxiang, Chen, Yijie, Chen, Ruiheng, Chen, Zhuliu, Wu, Chenyu, Ding, Jian, Xu, Yu, Jiang, Jingtao, Xu, Huazi, Zhu, Xuwei, Gao, Weiyang, Zhou, Kailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060706/
https://www.ncbi.nlm.nih.gov/pubmed/33898433
http://dx.doi.org/10.3389/fcell.2021.643996