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Comprehensive Preclinical Assessment of ADVM-022, an Intravitreal Anti-VEGF Gene Therapy for the Treatment of Neovascular AMD and Diabetic Macular Edema

Inhibition of vascular endothelial growth factor is the mode of action for several approved therapies, including aflibercept, for the treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). Lack of compliance due to the frequent intravitreal dosing requirem...

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Detalles Bibliográficos
Autores principales: Gelfman, Claire M., Grishanin, Ruslan, Bender, Kristina Oresic, Nguyen, Aivan, Greengard, Judith, Sharma, Pallavi, Nieves, Julio, Kiss, Szilárd, Gasmi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060718/
https://www.ncbi.nlm.nih.gov/pubmed/33835848
http://dx.doi.org/10.1089/jop.2021.0001