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Comprehensive Preclinical Assessment of ADVM-022, an Intravitreal Anti-VEGF Gene Therapy for the Treatment of Neovascular AMD and Diabetic Macular Edema
Inhibition of vascular endothelial growth factor is the mode of action for several approved therapies, including aflibercept, for the treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). Lack of compliance due to the frequent intravitreal dosing requirem...
Autores principales: | Gelfman, Claire M., Grishanin, Ruslan, Bender, Kristina Oresic, Nguyen, Aivan, Greengard, Judith, Sharma, Pallavi, Nieves, Julio, Kiss, Szilárd, Gasmi, Mehdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060718/ https://www.ncbi.nlm.nih.gov/pubmed/33835848 http://dx.doi.org/10.1089/jop.2021.0001 |
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