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ROS-associated mechanism of different concentrations of pinacidil postconditioning in the rat cardiac Nrf2-ARE signaling pathway

Previous studies have confirmed that 50 µmol/l pinacidil postconditioning (PPC) activates the nuclear factor-E2 related factor 2 (Nrf2)-antioxidant responsive element (ARE) pathway, which protects the myocardium from ischemia-reperfusion (IR) injury; however, whether this is associated with reactive...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Deng, Mengyuan, Wang, Haiying, Wang, Ying, Zhou, Wenjing, Yu, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060791/
https://www.ncbi.nlm.nih.gov/pubmed/33846798
http://dx.doi.org/10.3892/mmr.2021.12072