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miR-654-5p inhibits autophagy by targeting ATG7 via mTOR signaling in intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is a common chronic disease characterized by the loss of extracellular matrix (ECM) in the nucleus pulposus (NP). Accumulating evidence has revealed that abnormal expression of microRNAs (miRs) is closely associated with IDD development. The present study aimed...

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Detalles Bibliográficos
Autores principales: Wang, Shanzheng, Guo, Yudong, Zhang, Xuejun, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060800/
https://www.ncbi.nlm.nih.gov/pubmed/33846806
http://dx.doi.org/10.3892/mmr.2021.12083