Cargando…
miR-654-5p inhibits autophagy by targeting ATG7 via mTOR signaling in intervertebral disc degeneration
Intervertebral disc degeneration (IDD) is a common chronic disease characterized by the loss of extracellular matrix (ECM) in the nucleus pulposus (NP). Accumulating evidence has revealed that abnormal expression of microRNAs (miRs) is closely associated with IDD development. The present study aimed...
Autores principales: | Wang, Shanzheng, Guo, Yudong, Zhang, Xuejun, Wang, Chen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060800/ https://www.ncbi.nlm.nih.gov/pubmed/33846806 http://dx.doi.org/10.3892/mmr.2021.12083 |
Ejemplares similares
-
Autophagy and mTOR signaling during intervertebral disc aging and degeneration
por: Yurube, Takashi, et al.
Publicado: (2020) -
Emerging role and therapeutic implication of mTOR signalling in intervertebral disc degeneration
por: Chen, Hai‐Wei, et al.
Publicado: (2022) -
BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells
por: Xiao, Quan, et al.
Publicado: (2022) -
RNA‐binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration
por: Shao, Zhenxuan, et al.
Publicado: (2020) -
miR-496, miR-1185, miR-654, miR-3183 and miR-495 are downregulated in colorectal cancer cells and have putative roles in the mTOR pathway
por: Alqurashi, Naif, et al.
Publicado: (2019)