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Itgb3-integrin-deficient mice may not be a sufficient model for patients with Glanzmann thrombasthenia

Itgb3-integrin-deficient (Itgb3(−/−)) mice have been reported as a Glanzmann thrombasthenia (GT) model and have been used for platelet research. However, it remains unclear whether this mouse model can fully simulate patients with GT or whether it has different characteristics from these patients. T...

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Detalles Bibliográficos
Autores principales: Li, Dongya, Peng, Jie, Li, Tiantian, Liu, Yichen, Chen, Min, Shi, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060805/
https://www.ncbi.nlm.nih.gov/pubmed/33880575
http://dx.doi.org/10.3892/mmr.2021.12088