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Itgb3-integrin-deficient mice may not be a sufficient model for patients with Glanzmann thrombasthenia
Itgb3-integrin-deficient (Itgb3(−/−)) mice have been reported as a Glanzmann thrombasthenia (GT) model and have been used for platelet research. However, it remains unclear whether this mouse model can fully simulate patients with GT or whether it has different characteristics from these patients. T...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060805/ https://www.ncbi.nlm.nih.gov/pubmed/33880575 http://dx.doi.org/10.3892/mmr.2021.12088 |