Association of Dual LRRK2 G2019S and GBA Variations With Parkinson Disease Progression

IMPORTANCE: Despite a hypothesis that harboring a leucine-rich repeat kinase 2(LRRK2) G2019S variation and a glucocerebrosidase (GBA) variant would have a combined deleterious association with disease pathogenesis, milder clinical phenotypes have been reported in dual LRRK2 and GBA variations Parkin...

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Detalles Bibliográficos
Autores principales: Ortega, Roberto A., Wang, Cuiling, Raymond, Deborah, Bryant, Nicole, Scherzer, Clemens R., Thaler, Avner, Alcalay, Roy N., West, Andrew B., Mirelman, Anat, Kuras, Yuliya, Marder, Karen S., Giladi, Nir, Ozelius, Laurie J., Bressman, Susan B., Saunders-Pullman, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060834/
https://www.ncbi.nlm.nih.gov/pubmed/33881531
http://dx.doi.org/10.1001/jamanetworkopen.2021.5845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060834/
https://www.ncbi.nlm.nih.gov/pubmed/33881531
http://dx.doi.org/10.1001/jamanetworkopen.2021.5845

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