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Structural Characterization of the SARS-Coronavirus Spike S Fusion Protein Core

The spike (S) glycoprotein of coronaviruses mediates viral entry into host cells. It is a type 1 viral fusion protein that characteristically contains two heptad repeat regions, denoted HR-N and HR-C, that form coiled-coil structures within the ectodomain of the protein. Previous studies have shown...

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Detalles Bibliográficos
Autores principales: Tripet, Brian, Howard, Megan W., Jobling, Michael, Holmes, Randall K., Holmes, Kathryn V., Hodges, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060857/
https://www.ncbi.nlm.nih.gov/pubmed/14996844
http://dx.doi.org/10.1074/jbc.M400759200