Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits

BACKGROUND: DNA methylation dynamics in the brain are associated with normal development and neuropsychiatric disease and differ across functionally distinct brain regions. Previous studies of genome-wide methylation differences among human brain regions focus on limited numbers of individuals and o...

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Detalles Bibliográficos
Autores principales: Rizzardi, Lindsay F., Hickey, Peter F., Idrizi, Adrian, Tryggvadóttir, Rakel, Callahan, Colin M., Stephens, Kimberly E., Taverna, Sean D., Zhang, Hao, Ramazanoglu, Sinan, Hansen, Kasper D., Feinberg, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061076/
https://www.ncbi.nlm.nih.gov/pubmed/33888138
http://dx.doi.org/10.1186/s13059-021-02335-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061076/
https://www.ncbi.nlm.nih.gov/pubmed/33888138
http://dx.doi.org/10.1186/s13059-021-02335-w

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