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Metabolic engineering strategy for synthetizing trans-4-hydroxy-l-proline in microorganisms

Trans-4-hydroxy-l-proline is an important amino acid that is widely used in medicinal and industrial applications, particularly as a valuable chiral building block for the organic synthesis of pharmaceuticals. Traditionally, trans-4-hydroxy-l-proline is produced by the acidic hydrolysis of collagen,...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenyu, Liu, Pengfu, Su, Weike, Zhang, Huawei, Xu, Wenqian, Chu, Xiaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061225/
https://www.ncbi.nlm.nih.gov/pubmed/33882914
http://dx.doi.org/10.1186/s12934-021-01579-2