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Metabolic engineering strategy for synthetizing trans-4-hydroxy-l-proline in microorganisms
Trans-4-hydroxy-l-proline is an important amino acid that is widely used in medicinal and industrial applications, particularly as a valuable chiral building block for the organic synthesis of pharmaceuticals. Traditionally, trans-4-hydroxy-l-proline is produced by the acidic hydrolysis of collagen,...
Autores principales: | Zhang, Zhenyu, Liu, Pengfu, Su, Weike, Zhang, Huawei, Xu, Wenqian, Chu, Xiaohe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061225/ https://www.ncbi.nlm.nih.gov/pubmed/33882914 http://dx.doi.org/10.1186/s12934-021-01579-2 |
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