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Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives

CRISPR gene drive systems offer a mechanism for transmitting a desirable transgene throughout a population for purposes ranging from vector‐borne disease control to invasive species suppression. In this simulation study, we assess the performance of several CRISPR‐based underdominance gene drive con...

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Detalles Bibliográficos
Autores principales: Champer, Jackson, Champer, Samuel E., Kim, Isabel K., Clark, Andrew G., Messer, Philipp W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061266/
https://www.ncbi.nlm.nih.gov/pubmed/33897820
http://dx.doi.org/10.1111/eva.13180