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Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosis

OBJECTIVE(S): Multiple sclerosis (MS) causes extensive damage in the hippocampus. Vitamin B12 (vit B12) and estradiol benzoate (EB) have anti-inflammatory and re-myelination properties that make them proper in improvement of cognitive impairment. This study aimed to evaluate the effects of these com...

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Detalles Bibliográficos
Autores principales: Taherian, Narjes, Vaezi, Gholamhassan, Neamati, Ali, Etemad, Leila, Hojjati, Vida, Gorji-Valokola, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061324/
https://www.ncbi.nlm.nih.gov/pubmed/33953866
http://dx.doi.org/10.22038/IJBMS.2021.51469.11681