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Multi‐compartment metabolomics and metagenomics reveal major hepatic and intestinal disturbances in cancer cachectic mice

BACKGROUND: Cancer cachexia is a multifactorial syndrome characterized by multiple metabolic dysfunctions. Besides the muscle, other organs such as the liver and the gut microbiota may also contribute to this syndrome. Indeed, the gut microbiota, an important regulator of the host metabolism, is alt...

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Detalles Bibliográficos
Autores principales: Pötgens, Sarah A., Thibaut, Morgane M., Joudiou, Nicolas, Sboarina, Martina, Neyrinck, Audrey M., Cani, Patrice D., Claus, Sandrine P., Delzenne, Nathalie M., Bindels, Laure B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061360/
https://www.ncbi.nlm.nih.gov/pubmed/33599103
http://dx.doi.org/10.1002/jcsm.12684