OTUD1 Activates Caspase‐Independent and Caspase‐Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation

Apoptosis‐inducing factor (AIF) plays a dual role in regulating cell survival and apoptosis, acting as a prosurvival factor in mitochondria via its NADH oxidoreductase activity and activating the caspase‐independent apoptotic pathway (i.e., parthanatos) after nuclear translocation. However, whether...

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Detalles Bibliográficos
Autores principales: Luo, Qingyu, Wu, Xiaowei, Zhao, Pengfei, Nan, Yabing, Chang, Wan, Zhu, Xiaolin, Su, Dan, Liu, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061361/
https://www.ncbi.nlm.nih.gov/pubmed/33898171
http://dx.doi.org/10.1002/advs.202002874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061361/
https://www.ncbi.nlm.nih.gov/pubmed/33898171
http://dx.doi.org/10.1002/advs.202002874

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