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OTUD1 Activates Caspase‐Independent and Caspase‐Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation
Apoptosis‐inducing factor (AIF) plays a dual role in regulating cell survival and apoptosis, acting as a prosurvival factor in mitochondria via its NADH oxidoreductase activity and activating the caspase‐independent apoptotic pathway (i.e., parthanatos) after nuclear translocation. However, whether...
Autores principales: | Luo, Qingyu, Wu, Xiaowei, Zhao, Pengfei, Nan, Yabing, Chang, Wan, Zhu, Xiaolin, Su, Dan, Liu, Zhihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061361/ https://www.ncbi.nlm.nih.gov/pubmed/33898171 http://dx.doi.org/10.1002/advs.202002874 |
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