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Dose‐Dependent Carbon‐Dot‐Induced ROS Promote Uveal Melanoma Cell Tumorigenicity via Activation of mTOR Signaling and Glutamine Metabolism

Uveal melanoma (UM) is the most common intraocular malignant tumor in adults and has a low survival rate following metastasis; it is derived from melanocytes susceptible to reactive oxygen species (ROS). Carbon dot (Cdot) nanoparticles are a promising tool in cancer detection and therapy due to thei...

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Detalles Bibliográficos
Autores principales: Ding, Yi, Yu, Jie, Chen, Xingyu, Wang, Shaoyun, Tu, Zhaoxu, Shen, Guangxia, Wang, Huixue, Jia, Renbing, Ge, Shengfang, Ruan, Jing, Leong, Kam W., Fan, Xianqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061404/
https://www.ncbi.nlm.nih.gov/pubmed/33898168
http://dx.doi.org/10.1002/advs.202002404