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Iron accumulation in skeletal muscles of old mice is associated with impaired regeneration after ischaemia–reperfusion damage

BACKGROUND: Oxidative stress is implicated in the insidious loss of muscle mass and strength that occurs with age. However, few studies have investigated the role of iron, which is elevated during ageing, in age‐related muscle wasting and blunted repair after injury. We hypothesized that iron accumu...

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Detalles Bibliográficos
Autores principales: Alves, Francesca M., Kysenius, Kai, Caldow, Marissa K., Hardee, Justin P., Crouch, Peter J., Ayton, Scott, Bush, Ashley I., Lynch, Gordon S., Koopman, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061412/
https://www.ncbi.nlm.nih.gov/pubmed/33665974
http://dx.doi.org/10.1002/jcsm.12685