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Clinical Significance of Shared T Cell Epitope Analysis in Early De Novo Donor-Specific Anti-HLA Antibody Production After Kidney Transplantation and Comparison With Shared B cell Epitope Analysis
In pre-sensitizing events, immunological memory is mainly created via indirect allorecognition where CD4(+) T cells recognize foreign peptides in the context of self-HLA class II (pHLA) presented on antigen-presenting cells. This recognition makes it possible for naive CD4(+) T-helper cells to diffe...
Autores principales: | Tomosugi, Toshihide, Iwasaki, Kenta, Sakamoto, Shintaro, Niemann, Matthias, Spierings, Eric, Nahara, Isao, Futamura, Kenta, Okada, Manabu, Hiramitsu, Takahisa, Takeda, Asami, Goto, Norihiko, Narumi, Shunji, Watarai, Yoshihiko, Kobayashi, Takaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061417/ https://www.ncbi.nlm.nih.gov/pubmed/33897684 http://dx.doi.org/10.3389/fimmu.2021.621138 |
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