An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development

The hippocampus is a brain area central for cognition. Mutations in the human SOX2 transcription factor cause neurodevelopmental defects, leading to intellectual disability and seizures, together with hippocampal dysplasia. We generated an allelic series of Sox2 conditional mutations in mouse, delet...

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Detalles Bibliográficos
Autores principales: Mercurio, Sara, Alberti, Chiara, Serra, Linda, Meneghini, Simone, Berico, Pietro, Bertolini, Jessica, Becchetti, Andrea, Nicolis, Silvia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061699/
https://www.ncbi.nlm.nih.gov/pubmed/33622105
http://dx.doi.org/10.1098/rsob.200339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061699/
https://www.ncbi.nlm.nih.gov/pubmed/33622105
http://dx.doi.org/10.1098/rsob.200339

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