Palmitoylation of Hedgehog proteins by Hedgehog acyltransferase: roles in signalling and disease

Hedgehog acyltransferase (Hhat), a member of the membrane-bound O-acyltransferase (MBOAT) family, catalyses the covalent attachment of palmitate to the N-terminus of Hedgehog proteins. Palmitoylation is a post-translational modification essential for Hedgehog signalling. This review explores the mec...

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Detalles Bibliográficos
Autor principal: Resh, Marilyn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061759/
https://www.ncbi.nlm.nih.gov/pubmed/33653085
http://dx.doi.org/10.1098/rsob.200414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061759/
https://www.ncbi.nlm.nih.gov/pubmed/33653085
http://dx.doi.org/10.1098/rsob.200414

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