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Central administration of sodium-glucose cotransporter-2 inhibitors increases food intake involving adenosine monophosphate-activated protein kinase phosphorylation in the lateral hypothalamus in healthy rats
INTRODUCTION: Sodium glucose cotransporter-2 (SGLT2) inhibitors are widely used for diabetes treatment. Although SGLT2 inhibitors have been clinically observed to increase food intake, roles or even the presence of SGLT2 in the central nervous system (CNS) has not been established. We aimed to eluci...
Autores principales: | Takeda, Kenji, Ono, Hiraku, Ishikawa, Ko, Ohno, Tomohiro, Kumagai, Jin, Ochiai, Hidetoshi, Matumoto, Ai, Yokoh, Hidetaka, Maezawa, Yoshiro, Yokote, Koutaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061802/ https://www.ncbi.nlm.nih.gov/pubmed/33879516 http://dx.doi.org/10.1136/bmjdrc-2020-002104 |
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