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4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N-(2,5-dioxopyrrolidin-1-yl) benzamide improves monoclonal antibody production in a Chinese hamster ovary cell culture

There is a continuous demand to improve monoclonal antibody production for medication supply and medical cost reduction. For over 20 years, recombinant Chinese hamster ovary cells have been used as a host in monoclonal antibody production due to robustness, high productivity and ability to produce p...

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Detalles Bibliográficos
Autores principales: Aki, Yuichi, Katsumata, Yuta, Kakihara, Hirofumi, Nonaka, Koichi, Fujiwara, Kenshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061942/
https://www.ncbi.nlm.nih.gov/pubmed/33886677
http://dx.doi.org/10.1371/journal.pone.0250416