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4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N-(2,5-dioxopyrrolidin-1-yl) benzamide improves monoclonal antibody production in a Chinese hamster ovary cell culture
There is a continuous demand to improve monoclonal antibody production for medication supply and medical cost reduction. For over 20 years, recombinant Chinese hamster ovary cells have been used as a host in monoclonal antibody production due to robustness, high productivity and ability to produce p...
Autores principales: | Aki, Yuichi, Katsumata, Yuta, Kakihara, Hirofumi, Nonaka, Koichi, Fujiwara, Kenshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061942/ https://www.ncbi.nlm.nih.gov/pubmed/33886677 http://dx.doi.org/10.1371/journal.pone.0250416 |
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