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Generation of cryopreserved macrophages from normal and genetically engineered human pluripotent stem cells for disease modelling

Macrophages are innate immune cells that play critical roles in tissue homeostasis, inflammation, and immune oncology. Macrophages differentiated from human induced pluripotent stem cells (iPSCs) overcome many limitations of using peripheral blood derived macrophages. The ability to scale up and cry...

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Detalles Bibliográficos
Autores principales: Munn, Christie, Burton, Sarah, Dickerson, Sarah, Bakshy, Kiranmayee, Strouse, Anne, Rajesh, Deepika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061979/
https://www.ncbi.nlm.nih.gov/pubmed/33886609
http://dx.doi.org/10.1371/journal.pone.0250107