Octreotide inhibits secretion of IGF-1 from orbital fibroblasts in patients with thyroid-associated ophthalmopathy via inhibition of the NF-κB pathway

PURPOSE: We investigated the effect of octreotide, a long-acting somatostatin (SST) analogue, on IGF-1 secretion and its possible mechanism of action in orbital fibroblasts (OFs) from patients with thyroid-associated ophthalmopathy (TAO). MATERIALS AND METHODS: OFs were isolated from the orbital fat...

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Detalles Bibliográficos
Autores principales: Kim, Sung Eun, Kim, Jia, Lee, Ji-Young, Lee, Seong-Beom, Paik, Ji-Sun, Yang, Suk-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062018/
https://www.ncbi.nlm.nih.gov/pubmed/33886620
http://dx.doi.org/10.1371/journal.pone.0249988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062018/
https://www.ncbi.nlm.nih.gov/pubmed/33886620
http://dx.doi.org/10.1371/journal.pone.0249988

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