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Minocycline decreases CCR2-positive monocytes in the retina and ameliorates photoreceptor degeneration in a mouse model of retinitis pigmentosa

Retinal inflammation accelerates photoreceptor cell death caused by retinal degeneration. Minocycline, a semisynthetic broad-spectrum tetracycline antibiotic, has been previously reported to rescue photoreceptor cell death in retinal degeneration. We examined the effect of minocycline on retinal pho...

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Detalles Bibliográficos
Autores principales: Terauchi, Ryo, Kohno, Hideo, Watanabe, Sumiko, Saito, Saburo, Watanabe, Akira, Nakano, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062037/
https://www.ncbi.nlm.nih.gov/pubmed/33886548
http://dx.doi.org/10.1371/journal.pone.0239108