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Minocycline decreases CCR2-positive monocytes in the retina and ameliorates photoreceptor degeneration in a mouse model of retinitis pigmentosa
Retinal inflammation accelerates photoreceptor cell death caused by retinal degeneration. Minocycline, a semisynthetic broad-spectrum tetracycline antibiotic, has been previously reported to rescue photoreceptor cell death in retinal degeneration. We examined the effect of minocycline on retinal pho...
Autores principales: | Terauchi, Ryo, Kohno, Hideo, Watanabe, Sumiko, Saito, Saburo, Watanabe, Akira, Nakano, Tadashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062037/ https://www.ncbi.nlm.nih.gov/pubmed/33886548 http://dx.doi.org/10.1371/journal.pone.0239108 |
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