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Hypomethylation mediates genetic association with the major histocompatibility complex genes in Sjögren’s syndrome

Differential methylation of immune genes has been a consistent theme observed in Sjögren’s syndrome (SS) in CD4+ T cells, CD19+ B cells, whole blood, and labial salivary glands (LSGs). Multiple studies have found associations supporting genetic control of DNA methylation in SS, which in the absence...

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Detalles Bibliográficos
Autores principales: Chi, Calvin, Taylor, Kimberly E., Quach, Hong, Quach, Diana, Criswell, Lindsey A., Barcellos, Lisa F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062105/
https://www.ncbi.nlm.nih.gov/pubmed/33886574
http://dx.doi.org/10.1371/journal.pone.0248429