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Hypomethylation mediates genetic association with the major histocompatibility complex genes in Sjögren’s syndrome
Differential methylation of immune genes has been a consistent theme observed in Sjögren’s syndrome (SS) in CD4+ T cells, CD19+ B cells, whole blood, and labial salivary glands (LSGs). Multiple studies have found associations supporting genetic control of DNA methylation in SS, which in the absence...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062105/ https://www.ncbi.nlm.nih.gov/pubmed/33886574 http://dx.doi.org/10.1371/journal.pone.0248429 |