Microbial genetic and transcriptional contributions to oxalate degradation by the gut microbiota in health and disease

Over-accumulation of oxalate in humans may lead to nephrolithiasis and nephrocalcinosis. Humans lack endogenous oxalate degradation pathways (ODP), but intestinal microbes can degrade oxalate using multiple ODPs and protect against its absorption. The exact oxalate-degrading taxa in the human microb...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Menghan, Devlin, Joseph C, Hu, Jiyuan, Volkova, Angelina, Battaglia, Thomas W, Ho, Melody, Asplin, John R, Byrd, Allyson, Loke, P'ng, Li, Huilin, Ruggles, Kelly V, Tsirigos, Aristotelis, Blaser, Martin J, Nazzal, Lama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062136/
https://www.ncbi.nlm.nih.gov/pubmed/33769280
http://dx.doi.org/10.7554/eLife.63642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062136/
https://www.ncbi.nlm.nih.gov/pubmed/33769280
http://dx.doi.org/10.7554/eLife.63642

Ejemplares similares