Rap1GAP Mediates Angiotensin II-Induced Cardiomyocyte Hypertrophy by Inhibiting Autophagy and Increasing Oxidative Stress

Abnormal autophagy and oxidative stress contribute to angiotensin II- (Ang II-) induced cardiac hypertrophy and heart failure. We previously showed that Ang II increased Rap1GAP gene expression in cardiomyocytes associated with hypertrophy and autophagy disorders. Using real-time PCR and Western blo...

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Detalles Bibliográficos
Autores principales: Gao, Yan, Zhao, Di, Xie, Wen-zhi, Meng, Tingting, Xu, Chunxiao, Liu, Yutong, Zhang, Pengfei, Bi, Xiuping, Zhao, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062190/
https://www.ncbi.nlm.nih.gov/pubmed/33936386
http://dx.doi.org/10.1155/2021/7848027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062190/
https://www.ncbi.nlm.nih.gov/pubmed/33936386
http://dx.doi.org/10.1155/2021/7848027

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