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TNF receptor-associated factor 6 (TRAF6) plays crucial roles in multiple biological systems through polyubiquitination-mediated NF-κB activation

NF-κB was first identified in 1986 as a B cell-specific transcription factor inducing immunoglobulin κ light chain expression. Subsequent studies revealed that NF-κB plays important roles in development, organogenesis, immunity, inflammation, and neurological functions by spatiotemporally regulating...

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Detalles Bibliográficos
Autores principales: YAMAMOTO, Mizuki, GOHDA, Jin, AKIYAMA, Taishin, INOUE, Jun-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062261/
https://www.ncbi.nlm.nih.gov/pubmed/33840674
http://dx.doi.org/10.2183/pjab.97.009