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Evaluation of dopamine D(3) receptor occupancy by blonanserin using [(11)C]-(+)-PHNO in schizophrenia patients

RATIONALE: Unlike other antipsychotics, our previous positron emission tomography (PET) study demonstrated that a single dose of blonanserin occupied dopamine D(3) as well as dopamine D(2) receptors in healthy subjects. However, there has been no study concerning the continued use of blonanserin. OB...

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Detalles Bibliográficos
Autores principales: Sakayori, Takeshi, Tateno, Amane, Arakawa, Ryosuke, Kim, Woo-chan, Okubo, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062348/
https://www.ncbi.nlm.nih.gov/pubmed/33180175
http://dx.doi.org/10.1007/s00213-020-05698-3