Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia

Chronic hypoxia is a major contributor to Chronic Kidney Disease (CKD) after Acute Kidney Injury (AKI). However, the temporal relation between the acute insult and maladaptive renal response to hypoxia remains unclear. In this study, we analyzed the time-course of renal hemodynamics, oxidative stres...

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Detalles Bibliográficos
Autores principales: Sánchez-Navarro, Andrea, Pérez-Villalva, Rosalba, Murillo-de-Ozores, Adrián Rafael, Martínez-Rojas, Miguel Ángel, Rodríguez‐Aguilera, Jesús Rafael, González, Norma, Castañeda-Bueno, María, Gamba, Gerardo, Recillas-Targa, Félix, Bobadilla, Norma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062449/
https://www.ncbi.nlm.nih.gov/pubmed/33888767
http://dx.doi.org/10.1038/s41598-021-88000-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062449/
https://www.ncbi.nlm.nih.gov/pubmed/33888767
http://dx.doi.org/10.1038/s41598-021-88000-5

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