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Tgf-β1 transcriptionally promotes 90K expression: possible implications for cancer progression

The 90K protein, also known as Mac-2 BP or LGALS3BP, can activate the immune response in part by increasing major histocompatibility (MHC) class I levels. In studies on a non-immune cell model, the rat FRTL-5 cell line, we observed that transforming growth factor (TGF)-β1, like γ-interferon (IFN), i...

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Detalles Bibliográficos
Autores principales: Grassadonia, Antonino, Graziano, Vincenzo, Pagotto, Sara, Veronese, Angelo, Giuliani, Cesidio, Marchisio, Marco, Lanuti, Paola, De Tursi, Michele, D’Egidio, Maurizia, Di Marino, Pietro, Brocco, Davide, Vici, Patrizia, De Lellis, Laura, Cama, Alessandro, Natoli, Clara, Tinari, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062489/
https://www.ncbi.nlm.nih.gov/pubmed/33888686
http://dx.doi.org/10.1038/s41420-021-00469-1