Scrt1, a transcriptional regulator of β-cell proliferation identified by differential chromatin accessibility during islet maturation

Glucose-induced insulin secretion, a hallmark of mature β-cells, is achieved after birth and is preceded by a phase of intense proliferation. These events occurring in the neonatal period are decisive for establishing an appropriate functional β-cell mass that provides the required insulin throughou...

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Detalles Bibliográficos
Autores principales: Sobel, Jonathan, Guay, Claudiane, Elhanani, Ofer, Rodriguez-Trejo, Adriana, Stoll, Lisa, Menoud, Véronique, Jacovetti, Cécile, Walker, Michael D., Regazzi, Romano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062533/
https://www.ncbi.nlm.nih.gov/pubmed/33888791
http://dx.doi.org/10.1038/s41598-021-88003-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062533/
https://www.ncbi.nlm.nih.gov/pubmed/33888791
http://dx.doi.org/10.1038/s41598-021-88003-2

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