G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic

Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a progressive neurodegenerative disease caused by point mutations in the gene for neuroserpin, a serine protease inhibitor of the nervous system. Different mutations are known that are responsible for mutant neuroserpin polymerizat...

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Detalles Bibliográficos
Autores principales: Ingwersen, Thies, Linnenberg, Christian, D’Acunto, Emanuela, Temori, Shabnam, Paolucci, Irene, Wasilewski, David, Mohammadi, Behnam, Kirchmair, Johannes, Glen, Robert C., Miranda, Elena, Glatzel, Markus, Galliciotti, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062559/
https://www.ncbi.nlm.nih.gov/pubmed/33888787
http://dx.doi.org/10.1038/s41598-021-88090-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062559/
https://www.ncbi.nlm.nih.gov/pubmed/33888787
http://dx.doi.org/10.1038/s41598-021-88090-1

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