Machine learning guided aptamer refinement and discovery

Aptamers are single-stranded nucleic acid ligands that bind to target molecules with high affinity and specificity. They are typically discovered by searching large libraries for sequences with desirable binding properties. These libraries, however, are practically constrained to a fraction of the t...

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Detalles Bibliográficos
Autores principales: Bashir, Ali, Yang, Qin, Wang, Jinpeng, Hoyer, Stephan, Chou, Wenchuan, McLean, Cory, Davis, Geoff, Gong, Qiang, Armstrong, Zan, Jang, Junghoon, Kang, Hui, Pawlosky, Annalisa, Scott, Alexander, Dahl, George E., Berndl, Marc, Dimon, Michelle, Ferguson, B. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062585/
https://www.ncbi.nlm.nih.gov/pubmed/33888692
http://dx.doi.org/10.1038/s41467-021-22555-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062585/
https://www.ncbi.nlm.nih.gov/pubmed/33888692
http://dx.doi.org/10.1038/s41467-021-22555-9

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