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Quantitative real-time analysis of the efflux by the MacAB-TolC tripartite efflux pump clarifies the role of ATP hydrolysis within mechanotransmission mechanism

Tripartite efflux pumps built around ATP-binding cassette (ABC) transporters are membrane protein machineries that perform vectorial export of a large variety of drugs and virulence factors from Gram negative bacteria, using ATP-hydrolysis as energy source. Determining the number of ATP molecules co...

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Detalles Bibliográficos
Autores principales: Souabni, Hager, Batista dos Santos, William, Cece, Quentin, Catoire, Laurent J., Puvanendran, Dhenesh, Bavro, Vassiliy N., Picard, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062640/
https://www.ncbi.nlm.nih.gov/pubmed/33888866
http://dx.doi.org/10.1038/s42003-021-01997-3