Histone dynamics mediate DNA unwrapping and sliding in nucleosomes

Nucleosomes are elementary building blocks of chromatin in eukaryotes. They tightly wrap ∼147 DNA base pairs around an octamer of histone proteins. How nucleosome structural dynamics affect genome functioning is not completely clear. Here we report all-atom molecular dynamics simulations of nucleoso...

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Detalles Bibliográficos
Autores principales: Armeev, Grigoriy A., Kniazeva, Anastasiia S., Komarova, Galina A., Kirpichnikov, Mikhail P., Shaytan, Alexey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062685/
https://www.ncbi.nlm.nih.gov/pubmed/33888707
http://dx.doi.org/10.1038/s41467-021-22636-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062685/
https://www.ncbi.nlm.nih.gov/pubmed/33888707
http://dx.doi.org/10.1038/s41467-021-22636-9

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