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MR1-Restricted MAIT Cells From The Human Lung Mucosal Surface Have Distinct Phenotypic, Functional, and Transcriptomic Features That Are Preserved in HIV Infection

Mucosal associated invariant T (MAIT) cells are a class of innate-like T cells that utilize a semi-invariant αβ T cell receptor to recognize small molecule ligands produced by bacteria and fungi. Despite growing evidence that immune cells at mucosal surfaces are often phenotypically and functionally...

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Detalles Bibliográficos
Autores principales: Khuzwayo, Sharon, Mthembu, Maphe, Meermeier, Erin W., Prakadan, Sanjay M., Kazer, Samuel W., Bassett, Thierry, Nyamande, Kennedy, Khan, Dilshaad Fakey, Maharaj, Priya, Mitha, Mohammed, Suleman, Moosa, Mhlane, Zoey, Ramjit, Dirhona, Karim, Farina, Shalek, Alex K., Lewinsohn, David M., Ndung’u, Thumbi, Wong, Emily B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062704/
https://www.ncbi.nlm.nih.gov/pubmed/33897687
http://dx.doi.org/10.3389/fimmu.2021.631410