Inhibition of Host Gene Expression by KSHV: Sabotaging mRNA Stability and Nuclear Export

Viruses are known for their ability to alter host gene expression. Kaposi sarcoma-associated herpesvirus has two proteins that obstruct host gene expression. KSHV SOX, encoded by the open reading frame 37 (ORF37), induces a widespread cytoplasmic mRNA degradation and a block on mRNA nuclear export....

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Detalles Bibliográficos
Autores principales: Pardamean, Carissa Ikka, Wu, Ting-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062738/
https://www.ncbi.nlm.nih.gov/pubmed/33898329
http://dx.doi.org/10.3389/fcimb.2021.648055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062738/
https://www.ncbi.nlm.nih.gov/pubmed/33898329
http://dx.doi.org/10.3389/fcimb.2021.648055

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