Cargando…

Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target

During tumor development and progression, intrinsic and extrinsic factors trigger endoplasmic reticulum (ER) stress and the unfolded protein response, resulting in the increased expression of molecular chaperones to cope with the stress and maintain tumor cell survival. Heat shock protein (HSP) GRP9...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Xiaofeng, Iwanowycz, Stephen, Ngoi, Soo, Hill, Megan, Zhao, Qiang, Liu, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062746/
https://www.ncbi.nlm.nih.gov/pubmed/33898309
http://dx.doi.org/10.3389/fonc.2021.629846