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Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target
During tumor development and progression, intrinsic and extrinsic factors trigger endoplasmic reticulum (ER) stress and the unfolded protein response, resulting in the increased expression of molecular chaperones to cope with the stress and maintain tumor cell survival. Heat shock protein (HSP) GRP9...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062746/ https://www.ncbi.nlm.nih.gov/pubmed/33898309 http://dx.doi.org/10.3389/fonc.2021.629846 |